• What is The Sinclair Method (TSM) and how does it work?
  The Sinclair Method pairs drinking with a prescribed opioid-blocker (most commonly naltrexone, sometimes nalmefene/Selincro). You take the tablet about an hour before you drink. By blocking alcohol’s endorphin reward, urges gradually reduce and control returns, a process often called pharmacological extinction. You do not have to be abstinent to start TSM.
• Who is TSM suitable for?
  Adults who want to reduce or regain control over their drinking without a forced abstinence start. A clinician will review your health, medications and any contraindications to confirm suitability.
• Do I need to stop drinking to begin?
  No. On TSM you take the medication before you drink. With consistent use, most people notice cravings and consumption reduce over time while maintaining control.
• What medications are used on TSM?
  UK prescribers typically use naltrexone or nalmefene (Selincro). Your doctor will recommend the most appropriate option during your consultation.
• How do I get started with Sinclair Method UK?
  Complete our short online suitability check. We’ll review your form and arrange a private doctor consultation to go through your plan, prescription and next steps.
• What does it cost?
  Programme options are listed on the Pricing page (currently £499 and £799). Medication cost is not included, it’s paid directly to the dispensing pharmacy (most clients pay ~£99 via our specialist pharmacy). See the Pricing page for full inclusions.
• Will you contact my GP or employer?
  No. We don’t contact your GP, employer or other agencies without your consent. Your information is used only to support your application and care. If clinical safety requires GP liaison, your clinician will discuss this with you first.
• Do I need a blood or liver function test (LFT)?
  No you don’t need an LFT to start. We can begin with your first 28 tablets without this. If you prefer, you can book bloods directly with us for £65 and (subject to results) receive a prescription for 168 tablets.
• What happens if I’m not medically suitable?
  If you’re not suitable after clinical assessment, our refund policy applies (minus any admin/consultation fees). In many cases, your clinician can prescribe a clinically appropriate alternative that works in a similar way to naltrexone.
• How long until I notice changes?
  It varies by person. Many notice early shifts within the first few weeks, with cravings and total units trending down over 1–3 months when the medication is taken correctly before drinking and guidance is followed.
• Are there side effects?
  As with any prescription medicine, side effects are possible and vary by person. Your doctor will review risks, interactions and suitability before prescribing and advise what to do if you experience any issues.
• What support is included?
  All programmes include a private doctor consultation and guidance; extended packages include longer one-to-one support. See the Pricing page for what’s included in each option.
• How do I book or ask something not covered here?
  Start with the online suitability check, or contact us with specific questions. During business hours we aim to reply within the hour (otherwise next working day).

Information on this page is for general guidance only and isn’t a substitute for medical advice. Your prescribing clinician will confirm suitability and next steps for you.