By Meike Leonard, Health Reporter | Published: 01:41, 7 December 2025 | Updated: 12:17, 8 December 2025

Millions could cut down on Christmas boozing with a £3 pill dubbed the 'Ozempic of alcohol', according to experts.

The medicine, called naltrexone, limits the pleasure-signals being sent out by the brain after an alcoholic drink, which reduces the desire to consume more.

80%
success rate with naltrexone
£3
cost per tablet
320k+
UK alcohol hospital admissions yearly

Research shows about four out of five people who take the tablet before consuming alcohol drastically reduce their intake or eliminate drinking altogether.

Just as weight-loss drugs, such as Ozempic and Mounjaro, reduce the craving for food, experts say naltrexone could be key in the fight against Britain's excessive festive consumption.

The Scale of Britain's Drinking Problem

Woman in control, looking contemplatively at untouched glass of wine

NHS guidelines advise no more than 14 units a week – roughly six pints of beer or ten small glasses of wine – yet a quarter of British adults regularly exceed this.

During December, two-thirds of Britons say they drink more than usual, leading to a spike in the number of people admitted to hospital for alcohol-related problems.

Naltrexone can be purchased privately for about £100 a month – but many users end up saving money by not buying alcohol.

UK Alcohol Statistics

  • Nearly a fifth of British adults admit to binge drinking in the past week
  • More than 320,000 people admitted to hospital yearly with alcohol-related conditions
  • Over 10,000 alcohol-related deaths per year – mostly from liver disease
  • Deaths linked to alcohol reached a record high last year
  • Regular drinking is a known risk factor for several cancers

How Naltrexone Works

The medication itself isn't new. In fact, it's been available on the NHS since the 1980s.

It works by blocking brain receptors where alcohol attaches so that the pleasurable buzz of drinking is reduced.

By reducing that effect, the brain 'unlearns' the link between alcohol and the production of feel-good chemicals that spark addiction and the urge to reach for a drink in the first place.

"This pill has been shown to reduce drinking so much more effectively than other therapies, like counselling and rehabilitation, and yet many GPs have never heard of it. It's really devastating for the vast number of people who are missing out." Dr Janey Merron, Sinclair Method UK

Studies show, when taken an hour before drinking, naltrexone has close to an 80 per cent success rate at getting users to drastically reduce or eliminate drinking altogether.

In comparison, rehabilitation methods – with Alcoholics Anonymous (AA) being the most widely used – yield success rates of less than 15 per cent, according to the World Health Organisation.

Expert Insight from Dr Janey Merron

Professional working mother at home office looking healthy and happy

Clinics usually offer the tablet alongside talking therapy and lifestyle advice. Within six months to a year, Dr Merron claims, most patients have reduced their drinking significantly – and, most importantly, don't feel compelled to drink too much even when they do have the rare tipple.

'At that point, your brain is basically reprogrammed to how it was before you ever started drinking in the first place,' says Dr Merron. 'So most people just aren't interested in drinking at all.'

Dr Merron argues the current NHS approach focuses too much on treating serious alcoholics and often ignores the millions of people who drink dangerous amounts but are not obviously addicted.

"My average patient isn't who you might think of when you picture an alcoholic. Many people who have an issue with drinking are high-functioning – often professionals, such as lawyers or bankers, or stressed mothers. Naltrexone should be available to treat anyone for whom alcohol has become a problem." Dr Janey Merron, Sinclair Method UK

Katie's Story: 'It's Been Miraculous'

Confident healthy woman walking outdoors on a winter morning

This was the case for East Midlands-based Katie, 37, who has asked us not to use her surname.

It was just after the birth of her second child that Katie – who runs her business from home, as well as homeschooling her children – began drinking frequently.

'I was drinking every night for weeks straight,' she says. 'And it was impacting my family.'

Desperate for a solution, Katie found the Sinclair Method, and naltrexone, while researching online. Now a couple of months into using the drug, she says it has been miraculous.

"It's doing something to my brain, I'm already drinking less, having far more sober days, and feel more mindful when I do drink. Looking back to where I was, I can hardly recognise myself now." Katie, 37, Sinclair Method UK patient

Could Naltrexone Work for You?

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Sinclair Method UK

The UK's leading provider of The Sinclair Method, offering medically supervised alcohol reduction programmes with a proven 80% success rate. Established 2014.