Cut down or stop at your own pace with one tablet before drinking, private doctor-led care and senior coach support.
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Sinclair Method UK Limited: founded in 2019, with training from Dr David Sinclair and Dr Roy Eskapa.
Learn why it matters Learn why it mattersYou're holding it all together - but drinking more than you want, more often than you'd like.
Every time you drink, your brain gets a hit of reward - so it learns to crave alcohol. The tablet blocks that reward. Keep drinking while it's working and, week by week, your brain unlearns the craving.
It's called pharmacological extinction, and it's backed by 90+ clinical trials.
See How It Works See How It WorksMedication is separate: £89-£99 per 28 tablets, delivered to your door.
from £49.58/month
around £1.63 a day
12 interest-free monthly payments with our finance partner humm. Total payable £595.
Subject to status and affordability check. UK residents 18+. Terms and conditions apply.Pay in 3 with Klarna or PayPal, or pay in full with major cards.
If our doctor decides the treatment isn't right for you, you get your money back minus a small clinical fee. And you're never alone - your dedicated coach is with you for the full 12 weeks.
Named clinicians, clear registration details and private support from a specialist team built around The Sinclair Method.
GP · GMC 4503868
GP · GMC 7406876
Prescribing Pharmacist · GPhC 2063769
Short, practical answers to the questions people usually need settled before they feel ready to book.
No. The Sinclair Method is different because you take the tablet before you drink. That drinking session is what allows your brain to unlearn the reward.
The medication is prescribed after a private clinical assessment. Your doctor checks suitability first and explains the important safety points before treatment starts.
Yes. Your support is confidential, private and delivered remotely. We do not inform your GP, employer or family without your permission.
If the doctor decides treatment is not suitable, you are refunded minus a small clinical fee. Your coach also supports you through the 12-week process.
The Sinclair Method is a proven, medical approach for cutting down on alcohol without the need for rehab or going cold turkey. After a private, confidential online consultation, you may be prescribed Naltrexone in the UK, a safe, non-addictive medication that helps reduce the urge to drink. TSM for alcohol treatment works quietly in the background, supporting you to regain control at your own pace and rebuild healthier habits. If Naltrexone is not right for you, our doctors will discuss other safe, evidence-based options.
Doctor-led assessment and guidance
Private, non-judgemental support
A Daily Mail feature on the Naltrexone "alcohol pill" and a recovery story supported by Sinclair Method UK.
Read Article
Esther Walker shares her journey of reducing alcohol consumption with the Sinclair Method, supported by Sinclair Method UK.
Read Article
Annabel Fenwick Elliott shares her ongoing progress in reducing alcohol intake with the Sinclair Method, supported by Sinclair Method UK.
Read ArticleThe Sinclair Method (TSM Alcohol) is for anyone who wants to take control of their drinking, whether your goal is to cut down, reduce alcohol cravings or stop altogether. If you are finding it difficult to change your drinking habits, want a private alternative to rehab or group programmes or are simply looking for a new approach that fits real life, this method could be the answer.
Every client receives a complete medical assessment and ongoing support tailored to their Sinclair Method journey.
Support is flexible, discreet and confidential. No group sessions are required unless you want them.
All prescriptions are non-addictive, evidence-based and designed to support real and lasting change.
With the Sinclair Method you take a tablet before you drink and gradually unlearn the habit.
No matter where you are on your journey, we offer clear programme pricing to help you
cut down or regain control of drinking at your own pace.
Every plan begins with a free online suitability check valid for 7
days. We will advise you if this treatment could be right for you before you make
any decisions.
12 interest-free monthly payments with humm. Total payable £595.
Subject to status and affordability check. UK residents 18+. Terms and conditions apply.TSM UK
12-Week
Guided Programme
or from
per month with humm
or 3 payments with Klarna or PayPal
TSM UK 12-Week Guided Programme
A structured, medically supported 12-week system designed to make taking naltrexone before drinking automatic, so your brain stops reinforcing the habit over time.
TSM UK
5-Month
Guided Programme
or over 3 months with Klarna or PayPal
TSM UK 5-Month Guided Programme
A structured, medically supported 5-month system designed to make taking naltrexone before drinking automatic, so your brain stops reinforcing the habit over time.
22+ Countries

Sinclair Method UK provides a remote-first support pathway for international clients, with clear onboarding and practical guidance at each step.
We support people across Europe, the Middle East, Asia-Pacific and the Americas with
structured consultations and country-aware communication.
Remote consultations and specialist guidance across time zones
Clear support pathways tailored for international clients
Donations to
Good Causes
Our mission is to help people make steady progress through a private step by step programme with respectful guidance.
Our approach combines documented science with practical insight from supporting thousands of clients.
Through continued charity support and outreach, we aim to create lasting impact for families and communities.
Start by filling out our free, confidential online suitability form. This quick first step helps us understand your goals and make sure the Sinclair Method is the right approach for you.
Schedule your private video or phone appointment with a dedicated GP. If suitable, you will receive your prescription for Naltrexone and expert support to get started.
Begin your journey to lasting change with one-to-one support from our experienced team. We are here to guide you every step of the way as you build healthier drinking habits and a better quality of life.